Hydroxypropyl Methylcellulose (HPMC): What Is It Used For? Hydroxypropyl methylcellulose (HPMC) is a semisynthetic polymer derived from cellulose, widely used in pharmaceuticals as an inactive ingredient. It serves multiple roles, including as a thickener, binder, film-former, and stabilizer in medications. While HPMC itself is not a drug, it is a critical component in many drug formulations to enhance efficacy, safety, and patient compliance. In oral tablets, HPMC acts as a binder to hold ingredients together and control the release of active compounds, ensuring slow absorption in the digestive tract. It is also used in ophthalmic solutions, such as artificial tears, to lubricate dry eyes and provide long-lasting relief. Topical creams and gels incorporate HPMC to improve texture and prolong contact with the skin. Additionally, HPMC is found in laxatives, where it absorbs water to form a gel-like substance, easing bowel movements. Its biocompatibility and non-toxic nature make it safe for most patients, though mild side effects like temporary blurred vision (eye drops) or bloating (oral use) may occur. Always consult a healthcare provider before using medications containing HPMC to ensure suitability and avoid interactions. In summary, HPMC is a versatile pharmaceutical excipient vital for optimizing drug delivery and performance.

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